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Available online at: (Accessed June 1, 2025)

NICE NG246 (2025) recommends lower BMI thresholds (27.5 instead of 30, and 24.5 instead of 27) for South Asian, Chinese, Other Asian, Middle Eastern, Black African, and African-Caribbean backgrounds, because type 2 diabetes risk rises at lower BMIs in these populations 3,5

It was the sound of her colon rupturing

A person weighing 300 pounds experiences a 1 mg dose differently than a person weighing 180 pounds, simply because the same amount of drug distributes across more tissue

This assessment may include reviewing your medication regimen, checking hormone levels (morning total testosterone in men with ED or low libido, thyroid function, prolactin when clinically indicated), evaluating for depression or anxiety, assessing cardiovascular health, and reviewing the adequacy of diabetes control if applicable

doi:10.1001/jamainternmed.2023.6663